Dermal Fillers

Dermal fillers injections are now routinely perform in aesthetic and dermatological clinics worldwide. Soft-tissue fillers have been employ in an increasingly wider range of indications, with hyaluronic acid (HA) now superseding other permanent (poly-methyl methacrylate) and nonpermanent filler materials (autologous fat, Poly-L-Lactic Acid (PLLA), Calcium Hydroxyapatite, collagen) due to its potential reversibility and remarkable biocompatibility.

There are many types of dermal fillers currently use for cosmetic and medical indications in routine clinical practice. Fillers can be classified as temporary, semipermanent, or permanent depending on the length of time the substance remains in tissue. They can also be classified by the composition of the product. Materials can be base on collagen (bovine, porcine, and human), hyaluronic acid, poly-L-lactic acid, calcium hydroxylapatite, polymethyl methacrylates, and polyacrylamide gels, among others. Temporary fillers are the products most often usedfor cosmetic purposes, in particular hyaluronic acid. This is due to the ease of application of fillers base on this substance, the good results obtained, and their safety profile.